New Pfizer Arthritis Drug passes 2nd Clinical Trial

Published by: Frank Galvano on 4th Mar 2011 | View all blogs by Frank Galvano
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New Pfizer Arthritis Drug passes 2nd Clinical Trial

Pfizer Inc announced on Friday that its new experimental drug for rheumatoid arthritis has met its main goals in a late-stage clinical trial.  It's a promising development for the world's largest pharmaceutical as it looks to offset losses from products that are set to lose patent protection.

The drug in question, tofacitinib, is one of Pfizer's most important new drugs.  The company has said the drug's safety profile is consistent with those seen in previous trials, and that no new safety concerns have been found.  The trial provided evidence that  tofacitinib reduces symptoms of rheumatoid arthritis by a statistically significant amount compared with placebo treatment at six months.  The drug also improved physical function in patients at three months, and increased incidents of remission at six months.

Patients who took part in the trial exhibited moderate to sever symptoms and had not responded adequately to traditional therapies.  The trial is the second of six late-stage trials and follow the results of the first, released in November.  Results from the final four trials are expected to be released by the middle of 2011.  One analyst said the drug could generate as much as $2 billion in annual slaes if it is eventually approved.

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